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time wore on, other priorities came along and the money that should have gone to replicating data and sending backups off-site was spent other ways Many of the organizations that needed to protect themselves have done little or nothing in the time since September 11, and that is a shame If there is another attack, it will be a great deal more than a shame Of course, technology has changed in the last 4 years We felt we needed to add a chapter about some new and popular technology related to the field of availability 8 is an overview of SANs, NAS, and storage virtualization We also added 22, which is a look at some emerging technologies Despite all of the changes in society, technology, and families, the basic principles of high availability that we discussed in the first edition have not changed.

6 shows typical calibration peaks found with bovine trypsin autolysis fragments15 154 BIOMOLECULE MOLECULAR WEIGHT DETERMINATION Electrospray ionization is the most commonly used ionization source for biomolecular studies In this ionization process, multiply charged ions are formed (without fragmentation), and this has two important consequences First, large molecules can be detected using MS equipment with low mass range; for example, an ion of mass 10,000 Da with 1 proton would be detected at m/z % 10,001, whereas the same ion with 9 additional protons will be detected in a different m/z position (%1001) Second, the multiplicity of peaks allows molecular weight estimation as a multiplepeak average by means of ad hoc computational algorithms, improving the precision of the resulting MW There are several computer algorithms, normally incorporated into the instrument software, used to calculate MW The algorithms are based on the following simple assumptions and calculations.

The mission statement that drove the first book still holds: You cannot achieve high availability by simply installing clustering software and walking away The technologies that systems need to achieve high availability are not automatically included by system and operating system vendors It s still difficult, complex, and costly We have tried to take a more practical view of the costs and benefits of high availability in this edition, making our Availability Index model much more detailed and prominent The technology chapters have been arranged in an order that maps to their positions on the Index; earlier chapters discuss more basic and less expensive examples of availability technology like backups and disk mirroring, while later chapters discuss more complex and expensive technologies that can deliver the highest levels of availability, such as replication and disaster recovery.

As much as things have changed since the first edition, one note that we included in that Preface deserves repeating here: Some readers may begrudge the lack of simple, universal answers in this book There are two reasons for this One is that the issues that arise at each site, and for each computer system, are different It is unreasonable to expect that what works for a 10,000employee global financial institution will also work for a 10-person law office We offer the choices and allow the reader to determine which one will work best in his or her environment The other reason is that after 15 years of working on, with, and occasionally for computers, I have learned that the most correct answer to most computing problems is a rather unfortunate, It depends.

If two adjacent peaks in the spectrum ( p1 and.

Once the process model is set, the work of the project execution teams consists of: setting the technical parameters for the process model; carrying out the required IT development; refining, validating and testing the resulting models; deploying the models on the production servers and making them available to the process actors..

Writing a book such as this one is a huge task, and it is impossible to do it alone I have been very fortunate to have had the help and support of a huge cast of terrific people Once again, my eternal love and gratitude go to my wonderful wife Carol, who puts up with all of my ridiculous interests and hobbies (like writing books), our beautiful daughters Hannah and Madeline, and our delightful son Jonathan Without them and their love and support, this book would simply not have been possible Thanks, too, for your love and support to my parents, Roberta and David Marcus, and my in-laws, Gladys and Herb Laden, who still haven t given me that recipe..