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When people speak of the end-to-end nature of availability, they usually think of all of the components between the user and the logically most distant server. While those components are, of course, all links in the chain of availability, they are still not the whole story. After all, either a piece of equipment is functioning, or it is not. If we maintain our user perspective on availability, another element needs to be considered: performance. Since our user cares about getting his job done on time, the performance of the system that he is attempting to use must also be considered. If the system is running but is so overloaded that its performance suffers or that it grinds to a halt, then the user who attempts to work will become frustrated, possibly more frustrated than he would if the system were down. So, in addition to monitoring system components to make sure they continue to function, system performance must be monitored from a user s perspective. Many system tools can be used to emulate the user experience, as well as to put artificial loads on systems so that high-water marks for acceptable levels of resource consumption can be determined. We believe, however, that benchmarks are not nearly as useful or practical as vendors would have you believe. In general, benchmarks can be tweaked and modified to get almost any desired results. At least one disk array vendor

Siuzdak, Mass Spectrometry for Biotechnology, Academic Press, New York, 1996, pp 35 41 8 R A W Johnstone and M E Rose, Mass Spectrometry for Chemists and Biochemists, Cambridge University Press, New York, 1996, pp 37, 54 9 S L Mullen and A G Maeshall, Anal Chim Acta 178, 1985, 17 26 10 A P Snyder, Interpreting Protein Mass Spectra, Oxford University Press, Oxford, UK, 2000, pp 87 110 11 M Mann, R C Hendrickson, and A Pandey Annu Rev Biochem 70, 2001, 437 473 12 C Dass, Principles and Practice of Biological Mass Spectrometry, Wiley-Intercience, New York, 2001, pp 83 84 13 G Siuzdak, Mass Spectrometry for Biotechnology, Academic Press, New York, 1996, pp 66 68 14 G Siuzdak, Mass Spectrometry for Biotechnology, Academic Press, New York, 1996, p 90 15 G Siuzdak, Mass Spectrometry for Biotechnology, Academic Press, New York, 1996, pp 22 24 16 C.

has a sales agreement that specifically prohibits its customers from running or publishing any benchmarks related to the vendor s equipment, and the vendor has enforced this prohibition in court on more than one occasion. Benchmarks rarely measure what people actually do on their systems. They seldom mimic multiuser systems, where users are working in a manner in which users actually work. And, unfortunately, benchmarks become less and less valid the more that the testing environment differs from reality, and it doesn t take a lot of differences to make the benchmark totally worthless. To a user who is trying to use a computer system, very little difference can be detected between a down system and a very slow one, and as the system slows down more and more, no difference is discernible at all. Back in the heyday of the Internet, an Internet consulting company, Zona Research, estimated that $4 billion a year was lost due to users attempting to buy things on slow web sites, then giving up and canceling their purchases. Although that number has surely come down in the time since the Internet boom, even a single cancelled transaction should be enough to give a company reason to stop and think.

Plus a change, plus c est la m me chose. (The more things change, the more they are the same.) Alphonse Karr (1849)

Dass, Principles and Practice of Biological Mass Spectrometry, Wiley-Interscience, New York, 2001, pp 125 128 17 For example, see http://pepseaprotanacom/ or http://wwwproteometricscom/ or http:// prowlrockefelleredu/cgi-bin/ProFound 18 W J Grif ths, A P Jonsson, S Liu, D K Rai, and Y Wang, Biochem J 355, 2001, 545 561 19 M Mann and M Wilm, Anal Chem 66, 1994, 4390 4399 20 For example, see http://wwwmannembl-heidelbergde/Services/PeptideSearchIntro html..

SOA is principally used in the development of applications that function in synchronous request/response mode a consumer calls the service offered by a producer and expects the most immediate possible response (it remains in place while awaiting the response) That said, the SOA can also be used in asynchronous mode a consumer calls the service offered by a producer, but does not remain in place while waiting for the response In this case, the result of the demand will subsequently be supplied to the consumer if the service contract specifies it, or supplied to a third-party service that continues the work thus begun An SOA therefore integrates asynchronous event-based management, which opens the way to one of the most promising aspects of the SOA approach: the orchestration of services for executing business processes.